On the appearance of carboxylates in electrostatic potential maps

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On the appearance of carboxylates in electrostatic potential maps.

Electron microscopy can provide accurate, high-resolution images of the distribution of electrostatic potential (ESP) in biological macromolecules. Careful examination of ESP maps that have been published for peptides and proteins at resolution ranging from 1.0 Å to 2.9 Å reveals that the negative charges of carboxylate groups have a profound effect on their appearance. It is clear that investi...

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ژورنال

عنوان ژورنال: Protein Science

سال: 2016

ISSN: 0961-8368

DOI: 10.1002/pro.3093